dr Dariusz Żurawek
Address:
Department of General Biochemistry
Faculty of Biochemistry, Biophysics and Biotechnology
Jagiellonian University
ul. Gronostajowa 7
30-387 Kraków
Room: C145
Phone: 12 664 62 18
E–mail: dariusz.zurawek@uj.edu.pl
Education and Titles:
2017 Institute of Pharmacology Polish Academy of Sciences, Kraków, Poland
Ph.D. (Medical Sciences; Discipline – medical biology) with Distinction
„The role of microRNA and aminergic systems in the stress resilience in an animal model of depression.”
2016 Academy of Music, Kraków, Poland
M.A. (Baroque cello player). “Selected stylistic and interpretation issues of the cello suite BWV 1009 through the prism of historically informed performance.”
2010 Jagiellonian University, Kraków, Poland
M.Sc. (Biology/Molecular Biology of the Cell)
“Quantitative measurements of binding of fluorescently labelled Concanavalin A in studies of heterogeneity of rat prostate cancer cell lines AT-2 and MatLyLu.”
Positions:
Since 2018 Faculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian University, Krakow, Poland
2013 – 2017 Institute of Pharmacology Polish Academy of Sciences, Kraków, Poland
Ph.D. Program
2010 – 2013 Institute of Pharmacology Polish Academy of Sciences, Kraków, Poland
Honors and awards:
2017 PhD thesis with distinction by the Council of Institute of Pharmacology Polish Academy of Sciences, Kraków, Poland
2017 START 2017 Award founded by Foundation for Polish Science - stipend for young, talented researchers at the outset of their career, who have already achieved some success in their field.
2013 ECNP Workshop for Junior Scientists in Europe, Nice, France – travel award for young scientist
2013 Roche Continents 2013 Youth, Arts, Science Award founded by Hoffmann – La Roche Ltd.
Courses and trainings:
2015 11th Poznań Summer School of Bioinformatics - Adam Mickiewicz University, Poland
Professional Society Membership:
Since 2018 Member, Polish Biochemical Society
Since 2016 Member, Polish Neuroscience Society
Subject of interest:
Molecular and biochemical dialogue between immunity, brain and behavior.
The role of stress in the development of different biochemical and molecular adaptations of an organism.
Regulation of miRNA biogenesis system under stress and inflammation.
microRNA in brain functioning and homeostasis.
Most significant publications:
1. Zurawek D, Gruca P, Antkiewicz-Michaluk L, Dziedzicka-Wasylewska M. (2019) Resilient phenotype in chronic mild stress paradigm is associated with altered expression levels of miR-18a-5p and serotonin 5-HT1a receptor in dorsal part of the hippocampus. Mol Neurobiol. 2019 May 16. doi: 10.1007/s12035-019-1622-2.
2. Zurawek D, Salerno-Kochan A, Dziedzicka-Wasylewska M, Nikiforuk A, Kos T, Popik P. (2018) Changes in the ex-pression of metabotropic glutamate receptor 5 (mGluR5) in a ketamine-based animal model of schizophrenia. Schizophr Res. 2017 Apr 19. pii: S0920-9964(17)30201-3.
3. Zurawek D, Kusmider M, Faron-Gorecka A, Gruca P, Pabian P, Solich J, Kolasa M, Papp M, Dziedzicka-Wasylewska M. (2017) Reciprocal MicroRNA Expression in Mesocortical Circuit and Its Interplay with Serotonin Transporter Define Resilient Rats in the Chronic Mild Stress. Mol Neurobiol. 54(8): 5741–5751.
4. Zurawek D, Kusmider M, Faron-Gorecka A, Gruca P, Pabian P, Kolasa M, Solich J, Szafran-Pilch K, Papp M, Dziedzicka-Wasylewska M. (2016) Time-dependent miR-16 serum fluctuations together with reciprocal changes in the expression level of miR-16 in mesocortical circuit contribute to stress resilient phenotype in chronic mild stress- An animal model of depression. Eur Neuropsychopharmacol. 26(1):23-36.
5. Zurawek D, Faron-Gorecka A., Kusmider M, Solich J, Kolasa M, Szafran-Pilch K, Kmiotek K, Gruca P, Papp M, Dziedzicka-Wasylewska M. (2015) Dopamine D1 and D2 Receptors in Chronic Mild Stress: Analysis of Dynamic Receptor Changes in an Animal Model of Depression Using In Situ Hybridization and Autoradiography [w] Dopamine Receptor Technologies, Neuromethods vol. 96. Tiberi M. (Ed.) Springer Science+Business Media New York 2015. ISBN 978-1-4939-2195-9.
6. Zurawek D, Faron-Górecka A, Kuśmider M, Kolasa M, Gruca P, Papp M, Dziedzicka-Wasylewska M. (2013) Mesolimbic dopamine D₂ receptor plasticity contributes to stress resilience in rats subjected to chronic mild stress. Psychopharmacology (Berl). 227(4):583-93.
Publications from last 4 years:
1. Zurawek D, Gruca P, Antkiewicz-Michaluk L, Dziedzicka-Wasylewska M. (2019) Resilient phenotype in chronic mild stress paradigm is associated with altered expression levels of miR-18a-5p and serotonin 5-HT1a receptor in dorsal part of the hippocampus. Mol Neurobiol. 2019 May 16. doi: 10.1007/s12035-019-1622-2.
2. Faron-Górecka A, Szlachta M, Kolasa M, Solich J, Górecki A, Kuśmider M, Żurawek D, Dziedzicka-Wasylewska M. (2019) Understanding GPCR dimerization. Methods Cell Biol. 149:155-178.
3. Faron-Górecka A, Kuśmider M, Solich J, Kolasa M, Pabian P, Gruca P, Romańska I, Żurawek D, Szlachta M, Papp M, Antkiewicz-Michaluk L, Dziedzicka-Wasylewska M. (2018) Regulation of somatostatin receptor 2 in the context of antidepressant treatment response in chronic mild stress in rat. Psychopharmacology (Berl). 235(7):2137-2149.
4. Kolasa M, Solich J, Faron-Górecka A, Żurawek D, Pabian P, Łukasiewicz S, Kuśmider M, Szafran-Pilch K, Szlachta M, Dziedzicka-Wasylewska M. (2018) Paroxetine and Low-dose Risperidone Induce Serotonin 5-HT1A and Dopa-mine D2 Receptor Heteromerization in the Mouse Prefrontal Cortex. Neuroscience. 377:184-196.
5. Szlachta M, Kuśmider M, Pabian P, Solich J, Kolasa M, Żurawek D, Dziedzicka-Wasylewska M, Faron-Górecka A. (2018) Repeated Clozapine Increases the Level of Serotonin 5-HT1AR Heterodimerization with 5-HT2A or Dopamine D2 Receptors in the Mouse Cortex. Front Mol Neurosci. 15;11:40.
6. Kuśmider M, Faron-Górecka A, Pabian P, Solich J, Szlachta M, Kolasa M, Żurawek D, Wójcikowski J, Daniel W, Dziedzicka-Wasylewska M. (2018) Effects of imipramine on cytokines panel in the rats serum during the drug treatment and discontinuation. Neurochem Int. 113:85-91.
7. Zurawek D, Salerno-Kochan A, Dziedzicka-Wasylewska M, Nikiforuk A, Kos T, Popik P. (2018) Changes in the ex-pression of metabotropic glutamate receptor 5 (mGluR5) in a ketamine-based animal model of schizophrenia. Schizophr Res. 2017 Apr 19. pii: S0920-9964(17)30201-3.
8. Zurawek D, Kusmider M, Faron-Gorecka A, Gruca P, Pabian P, Solich J, Kolasa M, Papp M, Dziedzicka-Wasylewska M. (2017) Reciprocal MicroRNA Expression in Mesocortical Circuit and Its Interplay with Serotonin Transporter Define Resilient Rats in the Chronic Mild Stress. Mol Neurobiol. 54(8): 5741–5751.
9. Szafran-Pilch K, Faron-Górecka A, Kolasa M, Żurawek D, Szlachta M, Solich J, Kuśmider M, Dziedzicka-Wasylewska M. (2017) Antidepressants promote formation of heterocomplexes of dopamine D2 and somatostatin subtype 5 receptors in the mouse striatum. Brain Res Bull. 5;135:92-97.
10. Szlachta M, Pabian P, Kuśmider M, Solich J, Kolasa M, Żurawek D, Dziedzicka-Wasylewska M, Faron-Górecka A. (2017) Effect of clozapine on ketamine-induced deficits in attentional set shift task in mice. Psychopharmacology (Berl). 234(14):2103-2112.
11. Faron-Górecka A, Kuśmider M, Szafran-Pilch K, Kolasa M, Żurawek D, Gruca P, Papp M, Solich J, Pabian P, Dziedzicka-Wasylewska M. (2017) Basal prolactin levels in rat plasma correlates with response to antidepressant treatment in animal model of depression. Neurosci Lett. 24;647:147-152.
12. Zurawek D, Kusmider M, Faron-Gorecka A, Gruca P, Pabian P, Kolasa M, Solich J, Szafran-Pilch K, Papp M, Dziedzicka-Wasylewska M. (2016) Time-dependent miR-16 serum fluctuations together with reciprocal changes in the expression level of miR-16 in mesocortical circuit contribute to stress resilient phenotype in chronic mild stress- An animal model of depression. Eur Neuropsychopharmacol. 26(1):23-36
13. Faron-Górecka A, Kuśmider M, Kolasa M, Żurawek D, Szafran-Pilch K, Gruca P, Pabian P, Solich J, Papp M, Dziedzicka-Wasylewska M. (2016) Chronic mild stress alters the somatostatin receptors in the rat brain. Psycho-pharmacology (Berl). 233(2):255-66.